Catalog

Polycythaemia vera

2A20.4

Link to WHO Definition

Polycythaemia vera – http://id.who.int/icd/entity/818364947

Polycythaemia vera (PV) is a clonal myeloproliferative neoplasm characterized by erythrocytosis frequently accompanied by leukocytosis, and/or thrombocytosis, and an associated increased risk of haemorrhagic and thrombotic (venous and arterial) complications. JAK2 p.V617F and JAK2 (Janus kinase 2) exon12 mutations have been strongly associated with PV.

Parents