Catalog
Autosomal dominant polycystic kidney disease
Link to WHO Definition
Autosomal dominant polycystic kidney disease – http://id.who.int/icd/entity/91220434
Multiple cysts in both kidneys increasing in number and size from adolescence, associated with development of hypertension and chronic renal failure. Autosomal dominant familial pattern is usual and due to mutations on chromosomes 16 and 4. Non-renal manifestations can include cysts in the liver and less commonly pancreas. Cerebral arterial aneurysms with subarachnoid haemorrhage, and other non-renal vascular abnormalities can also occur.