102036-1

LOINC 2.82

Abnormal Prion Protein [Interpretation] in Cerebral spinal fluid Document by RT-QuIC

Abn Prion Prot CSF Doc RT-QuIC-Imp

Definition

  • Transmissible spongiform encephalopathies (TSEs or prion diseases) are a rare group of invariably fatal neurodegenerative disorders that affect humans and other mammals. TSEs are protein misfolding diseases that involve the accumulation of an abnormally aggregated form of the normal host prion protein (PrP). They are unique among protein misfolding disorders in that they are transmissible and have different strains of infectious agents that are associated with unique phenotypes in vivo. https://pubmed.ncbi.nlm.nih.gov/19157856/#:~:text=Abstract,host%20prion%20protein%20(PrP).

Component

  • Prion protein.abnormal

Specimen / system

  • CSF

Class

  • MICRO

Property

  • Imp

Scale

  • Doc

Method

  • RT-QuIC

Related names

  • abn; Abn Prion Prot; abnorm; Bovine spongiform encephalopathy; BSE; Cerebral spinal fluid; Cerebrospinal Fl; Document; Impression; Impression/interpretation of study; Impressions; Interp; Interpretation; Microbiology; Point in time; PR; Prot; PrP; Random; Scrapie; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid

Index terms

  • abn
  • Abn Prion Prot
  • abnorm
  • Bovine spongiform encephalopathy
  • BSE
  • Cerebral spinal fluid
  • Cerebrospinal Fl
  • Document
  • Impression
  • Impression/interpretation of study
  • Impressions
  • Interp
  • Interpretation
  • Microbiology
  • Point in time
  • PR
  • Prion protein.abnormal
  • Prot
  • PrP
  • Random
  • Scrapie
  • Spinal Fl
  • Spinal Fld
  • Spinal Flu
  • Spinal Fluid