Leukocyte deformability sepsis assessment [Interpretation] in Blood by Microfluidic deformability cytometer

Lukcyt deform sepsis assessmnt Bld Microfluid deform cytmtr-Imp

Definition

This term represents a test which measures biophysical and morphological changes in leukocytes (white blood cells) that occur during immune activation and dysregulation, with a specific focus on detecting sepsis. The test analyzes circulating neutrophils, monocytes, and other white blood cells using microfluidic technology to quantify cellular mechanical properties-particularly visco-elastic inertial response (VEIR): which reflects cell density, size, deformability, and viscosity. These biophysical properties change dramatically during leukocyte activation, including nuclear rearrangement and the early stages of neutrophil extracellular trap (NET) formation, processes characteristic of dysregulated immunity in sepsis. [PMID:37189536]

Blood; CELL MARKERS; Impression; Impression/interpretation of study; Impressions; Interp; Interpretation; Leuc; Leuk; Leukocytes; Lkcs; Lukcyt deform sepsis assessmnt; Microfluid deform cytmtr; Point in time; Random; WB; WBC; WBCs; White blood cell; White blood cells; Whole blood