49010-2

LOINC 2.82

Platelet aggregation [Units/volume] in Platelet rich plasma by ADP induced

PA PRP ADP-aCnc

Definition

  • Assay is used to measure platelet P2Y12 receptor blockade known to occur with some drugs including the thienopyridine class of drugs, including clopidogrel (Plavis(r)). VerifyNow P2Y12 Assay from Accumetrics uses adenosine-5-diphosphate(ADP/PGE1) to induce platelet activation. Activated platelets bind fibrinogen in proportion to the number of expressed platelet GPIIb/IIIa receptors. Light transmittance increases as activated platelets bind and aggregate the fibrinogen-coated beads. A turbidimetric based optical detection system measures change in optical signal caused by aggregation and reports results in P2Y12 Reaction Units(PRU). Information from VerifyNow P2Y12 Assay package insert from Accumetrics dated 2006 09 01

Component

  • Platelet aggregation

Specimen / system

  • PRP

Class

  • COAG

Property

  • ACnc

Scale

  • Qn

Method

  • Aggregometry.adenosine diphosphate induced

Related names

  • ADP; Agg; Aggr; ANED; Arbitrary concentration; COAGULATION; Hematology; Heme; Medication stress; PA; Pl; Platelet rich plasma; Platelets; Platelt; Plt; Point in time; QNT; Quan; Quant; Quantitative; Random; Thrombocyte; Thrombocytes

Index terms

  • ADP
  • Agg
  • Aggr
  • ANED
  • Arbitrary concentration
  • COAGULATION
  • Hematology
  • Heme
  • Medication stress
  • PA
  • Pl
  • Platelet rich plasma
  • Platelets
  • Platelt
  • Plt
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • Thrombocyte
  • Thrombocytes