66880-6

LOINC 2.82

Skin Ab.IgG pattern [Interpretation] in Serum by Monkey esophagus substrate

Skin Ab.IgG pattern Ser Monkey esoph-Imp

Definition

  • The detection of skin antibodies assists in the diagnosis of chronic vesicular-bullous diseases such as pemphigus and pemphigoid. When patient sera are incubated on monkey or guinea pig esophagus sections, anti-skin antibodies present in the serum will bind with disease-specific patterns by immunofluorescence. For example, the intercellular (IC) antibody pattern diagnoses pemphigus with a 90% sensitivity. Testing with the 2 different species of esophagus sections (monkey and guinea pig) assists in distinguishing different forms of pemphigus. Antibodies following a basement membrane pattern are present in bullous pemphigoid (70%), vesicular pemphigoid (50%) and cicatricial pemphigoid (10%).

Component

  • Skin Ab.IgG pattern

Specimen / system

  • Ser

Class

  • SERO

Property

  • Imp

Scale

  • Nom

Method

  • Monkey esophagus substrate

Related names

  • Immune globulin G; Immunoglobulin G; Impression; Impression/interpretation of study; Impressions; Integument; Interp; Interpretation; Nominal; Point in time; Random; Serology; Serum; SR

Index terms

  • Immune globulin G
  • Immunoglobulin G
  • Impression
  • Impression/interpretation of study
  • Impressions
  • Integument
  • Interp
  • Interpretation
  • Nominal
  • Point in time
  • Random
  • Serology
  • Serum
  • SR