Nuclear IgG Ab [Ratio] in Serum by Immunoassay

Nuclear IgG Ser IA-Rto

Definition

This term was created for (but not limited to) Euroimmun's ANA Screen ELISA (IgG) test kit, a semi-quantitative in vitro assay of a pool of human nuclear autoantibodies (IgG) against ten different antigens, including double-stranded DNA (dsDNA), histones, ribosomal P-proteins, nRNP, Sm, SS-A, SS-B, Scl-70, Jo-1 and centromeres. Semi-quantitative results are determined by the ratio of the extinction of the calibrator (cut-off) to the extinction of control or patient samples. A ratio of 1.0 or greater is a positive result, which is associated conditions such as Sharp syndrome (MCTD), Systemic lupus erythematosus, Sjögren's syndrome, Progressive systemic sclerosis, and Poly-dermatomyositis.

ABS; Aby; ANA; ANA IgG; ANF; Antby; Anti; Antibodies; Antibody; Antinuclear antibody; Autoantibodies; Autoantibody; EIA; ELFA; ELISA; Enzyme immunoassay; IAA; Immune globulin G; Immunoglobulin G; MEIA; NA; Nuc; Point in time; QNT; Quan; Quant; Quantitative; Random; Ratios; Rto; Serology; Serum; SR; SUDS