TF gene full mutation analysis in Blood or Tissue by Sequencing

TF gene Full Mut Anl Bld/T Seq

Definition

Transferrin (TF) gene sequencing may be performed in conjunction with a Carbohydrate Deficient Transferrin (CDT) assay to rule out accusations of excessive alcohol consumption. CDT assays are used to identify and monitor individuals who have been charged with excessive alcohol consumption. However, some patients who have certain variants in the TF gene are unable to add the carbohydrate chain to the transferrin protein. This makes them carbohydrate deficient even if they are not consuming alcohol. Identification of specific variants in the TF gene support the lack of alcohol consumption.

Blood; CD142; coagulation factor III (thromboplastin, tissue factor); Document; Finding; Findings; full gene sequencing; Full Mut Anl; Genetics; Heredity; Heritable; high-throughput sequencing; HTS; Inherited; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Mut; Mutations; Next generation sequencing; NGS; Point in time; Random; sequencing of entire coding region; TF; TFA; Tissue; Tissue, unspecified; transferrin; WB; Whole blood; Whole blood or Tissue