72503-6LOINC 2.82
WT1 gene exon 1+2 transcript/control transcript [# Ratio] in Blood or Tissue by Molecular genetics method
WT1 ex 1+2/control Bld/T
Definition
- Wilm's tumor (WT1) gene expression is calculated by measuring the copy numbers of transcripts within exon 1 and 2 of the WTI gene compared to transcripts from a control gene. The WT1 gene expression is used as a specific molecular marker to improve diagnosis, prognosis and follow-up of adult acute myeloid leukemia (AML) patients. Early decreased expression of WT1 copy number in peripheral blood predicts better outcome for AML patients [PMID:20107153]. This code is based on, but not limited in use to, the submitter's package insert, Ipsogen's ProfileQuant® kit. This kit uses real-time quantitative PCR to quantify WT1 gene expression relative to ABL1 control gene.
Component
- WT1 gene exon 1+2 transcript/control transcript
Specimen / system
- Bld/Tiss
Class
- MOLPATH.MUT
Property
- NRto
Scale
- Qn
Method
- Molgen
Related names
- ABL; ABL1; ABL1 transcript; AWT1; Blood; control gene; EWS-WT1; Genetics; GUD; Heredity; Heritable; i; II; Inherited; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; NPHS4; Number ratio; PCR; Point in time; QNT; Quan; Quant; Quantitative; Random; Tissue; Tissue, unspecified; WAGR; WB; Whole blood; Whole blood or Tissue; Wilms tumor 1; WIT-2; WT1 ex 1+2; WT33
Index terms
- ABL
- ABL1
- ABL1 transcript
- AWT1
- Blood
- control gene
- EWS-WT1
- Genetics
- GUD
- Heredity
- Heritable
- i
- II
- Inherited
- Molecular genetics
- Molecular pathology
- MOLPATH
- MOLPATH.MUTATIONS
- NPHS4
- Number ratio
- PCR
- Point in time
- QNT
- Quan
- Quant
- Quantitative
- Random
- Tissue
- Tissue, unspecified
- WAGR
- WB
- Whole blood
- Whole blood or Tissue
- Wilms tumor 1
- WIT-2
- WT1 ex 1+2
- WT33