72518-4

LOINC 2.82

CHEK2 gene c.470C>T and 1100delC [Identifier] in Blood or Tissue by Molecular genetics method Nominal

CHEK2 c.470C>T+1100delC Bld/T

Definition

  • Targeted mutation analysis for the variant 470C>T (I157T, [NCBI dbSNP ID: rs17879961]) in exon 3 and the 1-base pair deletion (1100delC) in exon 10 of the CHEK2 gene is performed for the diagnosis of various cancers, including breast, ovarian, colorectal and prostate cancer.

Component

  • CHEK2 gene.c.470C>T & 1100delC

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH.MUT

Property

  • Prid

Scale

  • Nom

Method

  • Molgen

Related names

  • Blood; CDS1; checkpoint kinase 2; CHEK2 c.470C>T+1100delC; CHK2; Genetics; hCds1; Heredity; Heritable; HuCds1; I157T; Identity or presence; Inherited; LFS2; Li-Fraumeni syndrome; Li-Fraumeni syndrome 2; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Nominal; PCR; Point in time; PP1425; RAD53; Random; rs17879961; T prime; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • Blood
  • CDS1
  • checkpoint kinase 2
  • CHEK2 c.470C&gt
  • CHEK2 gene.c.470C>T & 1100delC
  • CHK2
  • Genetics
  • hCds1
  • Heredity
  • Heritable
  • HuCds1
  • I157T
  • Identity or presence
  • Inherited
  • LFS2
  • Li-Fraumeni syndrome
  • Li-Fraumeni syndrome 2
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • MOLPATH.MUTATIONS
  • Nominal
  • PCR
  • Point in time
  • PP1425
  • RAD53
  • Random
  • rs17879961
  • T prime
  • T+1100delC
  • Tissue
  • Tissue, unspecified
  • WB
  • Whole blood
  • Whole blood or Tissue