dic(9;20)(p11-13;q11)(wcp9+,wcp20+) [Identifier] in Blood or Tissue by FISH Nominal

dic(9;20)(wcp9+,wcp20+) Bld/T FISH

Definition

FISH techniques, such as whole chromosome painting (WCP) using a mixture of probes, is performed to identify a rare dicentric chromosome abnormality, dic(9;20)(p11-13;q11). This abnormality occurs in leukemia patients and may be specifically associated with acute lymphoblastic leukemia (ALL). The presence of the aberration is important for coordinating adequate therapy. The submitter's lab reports the X number of cells that have the probe deletion out of Y number of cells, which is usually 100% when present. Results are typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format.

Acute lymphoblastic leukaemia; ALL; Blood; dic(9;20)(wcp9+,wcp20+); Fluorescent in situ hybridization; Genetics; Heredity; Heritable; Identity or presence; Inherited; Molecular pathology; MOLPATH; Nominal; Point in time; Random; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue; whole chromosome paint