CYP2B6 gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

CYP2B6 allele Geno Bld/T

Definition

A patient's genotype for the CYP2B6 gene is typically reported as *A/*B where A is the allele from one chromosome and B is the allele from the other chromosome. The genotype is determined by the analysis of specific single nucleotide polymorphisms (SNPs) within the gene by various molecular techniques, including PCR and microarray. A number of variants within this gene are associated with altered drug metabolism have been described, including *8 (415A>G), *9 (516G>T), *16 (983T>C), and *5 (1459C>T). In some cases, SNP results are analyzed by bioinformatics computer software to determine a patient's overall genotype.

Blood; CPB6; CYP2B; CYP2B6 allele; CYP2B7; CYP2B7P; CYPIIB6; cytochrome P450, family 2, subfamily B, polypeptide 6; EFVM; Genetics; Heredity; Heritable; IIB1; Inherited; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.PHARMG; Nominal; P450; PCR; Point in time; Random; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue