Gamma interferon negative control spot count [#] in Blood

IGNF neg cntrl Bld

Definition

The count of negative control spots (0 to >20) in a patient's T cells incubated without M. tuberculosis antigens (ESAT-6, CFP10). This term is created for, but not limited in use to, Oxford Immunotec's T-SPOT.TB assay, used to diagnose M. tuberculosis. T-SPOT.TB assay uses enzyme-linked immunospot (ELISPOT) methodology to enumerate M. tuberculosis-sensitized T cells by capturing interferon-gamma (IFN-y) in the vicinity of T cells in the patient's whole blood. In the T-SPOT.TB test, a typical result is expected to have few to no spots in the negative (nil) control and 20 or more spots in the positive control (Mitogen stimulated). A negative control spot count of >10 is considered invalid.

Blood; Cnt; Count; ID; IFN; IGNF neg cntrl; IGNF neg control; Infectious Disease; InfectiousDisease; Lung; Microbiology; NEG; Number; Point in time; Pulmonary; Pulmonology; QNT; Quan; Quant; Quantitative; Random; Respiratory; WB; Whole blood