Porphyrin fractions panel - Stool

Porphyrin Fract Pnl SFr Stl

Definition

Determination of porphyrin profile in stool is performed to evaluate porphyria. Total fecal porphyrins are markedly increased especially in active HCP (Hereditary Coproporphyria) and VP (Variegate Porphyria) and to a lesser extent in PCT (Porphyria Cutanea Tarda) and EPP (Erythropoietic Protoporphyria). Porphyrins with 2-4 carboxyl groups generally predominate in feces. As with urine, it is most useful to measure the total amount of porphyrins in a fecal sample. If increased, then the laboratory may determine which porphyrins predominate to identify the presence and nature of the porphyrin defect. A summary of the different porphyria disorders, the genes where mutations occur and the associated symptoms is given in: http://www.porphyria-europe.com/02-for-healthcare/the-porphyrias.asp.

Bowel movement; Chemistry; Faecal; Faeces; Fecal; Feces; Frac; Fract; Fraction; Fractionated; Fractionation; Pan; PANEL.CHEMISTRY; Panl; Percent; Pnl; Point in time; Porphyrin Fract Pnl; Random; Stl; Stool = Fecal; Substance Fraction