74866-5

LOINC 2.82

IgM.kappa [Mass/volume] in Serum or Plasma

IgM kappa SerPl-mCnc

Definition

  • Immunoglobulins are made up of two identical heavy chains which define the immunoglobulin class (A, G, or M) and two identical light chains, kappa or lambda (κ or λ). Each light chain is bound to a heavy chain. This test measures IgM, but selectively IgM with a kappa light chain. The assay employs antibodies that target unique junctional epitopes between the light and heavy chains for each Ig molecule. High serum concentrations of monoclonal protein may indicate an underlying abnormality such as multiple myeloma, monoclonal gammopathy of unknown significance (MGUS), or other lymphoproliferative disorders. [PMID:23211046] This term was based on, but not limited in use to, the Hevylite Human IgM Kappa assay.

Component

  • IgM.kappa

Specimen / system

  • Ser/Plas

Class

  • CHEM

Property

  • MCnc

Scale

  • Qn

Related names

  • Chemistry; IgM kappa; Immune globulin M; Immunoglobulin M; Level; Mass concentration; Pl; Plasma; Plsm; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR

Index terms

  • Chemistry
  • IgM kappa
  • Immune globulin M
  • Immunoglobulin M
  • Level
  • Mass concentration
  • Pl
  • Plasma
  • Plsm
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • SerP
  • SerPl
  • SerPlas
  • Serum
  • Serum or plasma
  • SR