Blood group antibody screen [Presence] in Serum or Plasma by Polyethylene glycol (PEG) method

Bld gp Ab Scn SerPl Ql PEG

Definition

Antibody screening is used to demonstrate unexpected antibodies (other than ABO) and is performed on both donors and recipients to help ensure compatibility between recipient antibodies and donor red cells. Polyethylene glycol (PEG) is a blood bank agent that reduces antibody screening incubation time by excluding water and therefore allowing red cells to come closer together during centrifugation. PEG may enhance the expression of warm antibodies and auto-antibodies. A downside to PEG is that use may lead to false positive reactions at 37C from nonspecific agglutination. An advantage of PEG use is that it may provide greater sensitivity than LISS or albumin.

Ab; Bld gp Ab Scn; BLOOD BANK; Ordinal; Pl; Plasma; Plsm; Point in time; Polyethylene Glycol; PR; QL; Qual; Qualitative; Random; Scn; Scr; Screen; Scrn; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR