Prothrombin activity [Units/volume] in Platelet poor plasma by Coagulation assay --immediately after addition of factor II depleted plasma

Prothrom imm FII DP PPP-aCnc

Definition

Tests for congenital or secondary deficiency of prothrombin (also called FII or factor II) by measuring prothrombin activity in patient plasma using a modified prothrombin time test (PT). Patient plasma is diluted and then added to a plasma deficient in prothrombin. Correction of the clotting time of the deficient plasma is proportional to the concentration (% activity) of that factor in the patient plasma, interpolated from a calibration curve. Prothrombin is a vitamin-K dependent plasma protein made in the liver and circulated in plasma. Congenital deficiency is very rare and usually causes minor bleeding. Secondary disorders are liver diseases, hyperfibrinolysis, disseminated intravascular coagulation (DIC), oral anticoagulant therapy, or vitamin-K deficiency. This term was created for, but not limited in use to, the HemolL Factor II deficient plasma test kit. Results may be expressed in % activity, IU/ml, or seconds.

2; Activ; Actvty; Arbitrary concentration; Clot; Clottable; COAGULATION; Coagulation assay; Coagulation factor II; Fac; Fact; Factor 2; Factor II; Factor II activity; FII; FII activity; Hematology; Heme; imm FII DP; Immediatedly after 1:1 addition of; Movements; Plas; Platelet poor plasma; Point in time; Prothombin; Prothrm; Prothromb; QNT; Quan; Quant; Quantitative; Random; Tilt tube