77217-8

LOINC 2.82

Salivary gland protein 1 and Carbonic anhydrase 6 and Parotid secretory protein IgA and IgG and IgM panel - Serum by Immunoassay

SP-1+CA6+PSP IgA+IgG+IgM Pnl Ser IA

Definition

  • Sjogren's disease is an autoimmune disease associated with kidney and lung disease as well as disorders of the salivary and lacrimal glands, which lead to problems with dry eyes and mouth. Sjogren's syndrome is associated with isolated salivary and lacrimal gland dysfunction and may be associated with other autoimmune disorders, such as systemic lupus erythematosus. Antibodies to salivary gland protein 1 (SP-1), carbonic anhydrase 6 (CA6) and parotid secretory protein (PSP) may be useful markers for identifying patients with Sjogren's disease or Sjogren's syndrome early in the course of disease and for those who have significant symptoms but are anti-Ro and anti-La antibody negative, which are two of the antibodies that are typically used to diagnose Sjogren's. Antibodies to SP-1, CA6 and PSP rarely occur in healthy controls or patients with other autoimmune disorders who do not have eye and mouth symptoms. [PMID: 23123440] This term was created for, but is not limited in use to, the IMMCO Diagnostics' early Sjogren's syndrome antibody profile, which includes terms for IgA, IgG and IgM antibodies to SP-1, CA6 and PSP.

Component

  • Salivary gland protein 1 & Carbonic anhydrase 6 & Parotid secretory protein Ab.IgA & IgG & IgM panel

Specimen / system

  • Ser

Class

  • PANEL.SERO

Property

  • -

Scale

  • Qn

Method

  • IA

Related names

  • CA6; EIA; ELFA; ELISA; Enzyme immunoassay; i; IAA; Immune globulin A; Immune globulin G; Immune globulin M; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; MEIA; Pan; PANEL.SEROLOGY; Panl; Pnl; Point in time; PR; Prot; PSP; QNT; Quan; Quant; Quantitative; Random; Serology; Serum; SP-1; SP-1+CA6+PSP; SP-1+CA6+PSP Ab; SP-1+CA6+PSP IgA+IgG+IgM; SP-1+CA6+PSP IgA+IgG+IgM Pnl; SR; SUDS

Index terms

  • CA6
  • EIA
  • ELFA
  • ELISA
  • Enzyme immunoassay
  • i
  • IAA
  • Immune globulin A
  • Immune globulin G
  • Immune globulin M
  • Immunoglobulin A
  • Immunoglobulin G
  • Immunoglobulin M
  • MEIA
  • Pan
  • PANEL.SEROLOGY
  • Panl
  • Pnl
  • Point in time
  • PR
  • Prot
  • PSP
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • Salivary gland protein 1 & Carbonic anhydrase 6 & Parotid secretory protein Ab.IgA & IgG & IgM panel
  • Serology
  • Serum
  • SP-1
  • SP-1+CA6+PSP
  • SP-1+CA6+PSP Ab
  • SP-1+CA6+PSP IgA+IgG+IgM
  • SP-1+CA6+PSP IgA+IgG+IgM Pnl
  • SR
  • SUDS