Influenza virus A H5 RNA [Cycle Threshold #] in Specimen by NAA with probe detection

FLUAV H5 RNA Ct Spec Qn NAA+probe

Definition

The goose/Guangdong lineage H5 viruses emerged in the late 90s in Asia and subsequently became the only lineage of viruses known to be highly pathogenic to poultry and sustained in wild birds. The World Health Organization recognizes these viruses under a unified H5 clade nomenclature. Viruses from this lineage, specifically clade 2.3.4.4, were introduced into North American flyways in late 2014 via the Bering Strait into the Pacific flyway and again in late 2021 into the Atlantic flyway. [PMID:25855748] The NALHN influenza A molecular assay (matrix 2009) works well for the detection of this viral clade and is the primary surveillance tool. As a screening tool, the NAHLN H5 assay does not distinguish geographic lineage nor pathotype (LPAI vs HPAI). This clade specific assay uses real-time reverse transcriptase PCR targeted to clade H5 2.3.4.4.

3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Avian influenza; Bird flu; DNA NUCLEIC ACID PROBE; DNA probe; FLUA; FLUAV; FLUAV H5; FLUV; Fowl plague; ID; Infectious Disease; InfectiousDisease; Influ; Influenza A; Influenza A virus; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; Misc; Miscellaneous; NAA+probe; NAAT; NASBA; Nucleic acid sequence based analysis; Other; PCR; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; QNT; Quan; Quant; Quantitative; Random; Ribonucleic acid; SDA; Spec; Strand Displacement Amplification; TMA; To be specified in another part of the message; Transcription mediated amplification; Unspecified; Vet; Veterinary

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