Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Peritoneal dialysis fluid by Immunoassay

NT-proBNP DiafP IA-mCnc

Definition

Brain natriuretic peptide (BNP) and amino-terminal proBNP (NT-proBNP) are significantly elevated in patients with heart failure because tension or stretching of the cardiac wall, such as occurs with heart failure, stimulates the synthesis of natriuretic peptides. Elevated levels are associated with adverse outcomes in both hemodialysis (HD) and peritoneal dialysis (PD) patients and are attributable to both ventricular dysfunction and decreased renal clearance. Peritoneal dialysate and plasma NT-proBNP levels are linearly related. [PMID: 21427249] This term was created for, but is not restricted in use to, the Elecsys proBNP II assay, which contains two monoclonal antibodies that recognize epitopes located in the N-terminal part (1-76) of proBNP (1-108).

Beta Natriuretic Peptide; BNP; Brain Natriuretic Peptide; B-type natriuretic peptide; Chemistry; Diaf; DiafP; Dialysate; Dialysis fluid; EIA; ELFA; ELISA; Enzyme immunoassay; IAA; Level; Mass concentration; MEIA; Natriutietic peptide.B; NTproBNP; NT-proBNP; Pept; Peritoneal Dialysis fluid; Point in time; proBNP; Pro-brain natriuretic peptide; QNT; Quan; Quant; Quantitative; Random; SUDS