78358-9

LOINC 2.82

Acyl CoA dehydrogenases [Enzymatic activity/mass] in Fibroblast by [9,10-3H] palmitate substrate

ACADs Fib Palmitate-cCnt

Definition

  • Fatty acid oxidation in medium- or long-chain acyl CoA dehydrogenase deficiencies can be measured by quantifying the release of 3H2O from (9,10-3H) palmitate (this term) and myristate [LOINC: 78360-5] substrates added to cultured fibroblast. [PMID: 2109149] Fatty acid (i.e. palmitate or myristate) oxidation rates by fibroblasts are expressed as nanomole of 3H fatty acid (3H FA) oxidized per hour per milligram of cell protein (nmol 3H FA/h/mg protein).[PMID: 12840153]

Component

  • Acyl CoA dehydrogenases

Specimen / system

  • Fibroblasts

Class

  • CHEM

Property

  • CCnt

Scale

  • Qn

Method

  • [9,10-3H] palmitate substrate

Related names

  • ACADs; Catalytic Content; Chemistry; Fib; Fibr; Point in time; QNT; Quan; Quant; Quantitative; Random

Index terms

  • ACADs
  • Catalytic Content
  • Chemistry
  • Fib
  • Fibr
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random