78958-6

LOINC 2.82

Cathepsin A [Enzymatic activity/mass] in Leukocytes

Cathepsin A WBC-cCnt

Definition

  • Cathepsin A enzyme activity in leukocytes is measured as part of a diagnostic work-up for galactosialidosis. Patients with galactosialidosis will have decreased activity of the protective protein as well as decreased neuraminidase and β-galactosidase activity in leukocytes (and/or fibroblasts). Sequencing of the CTSA gene is performed for detection of disease-causing mutations.

Component

  • Cathepsin A

Specimen / system

  • WBC

Class

  • CHEM

Property

  • CCnt

Scale

  • Qn

Related names

  • Catalytic Content; Chemistry; Galactosialidosis; Galactosidase; Leukocytes; Lysosomal Protective Protein; Point in time; QNT; Quan; Quant; Quantitative; Random; WBCs; White blood cells

Index terms

  • Catalytic Content
  • Chemistry
  • Galactosialidosis
  • Galactosidase
  • Leukocytes
  • Lysosomal Protective Protein
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • WBCs
  • White blood cells