79298-6

LOINC 2.82

D- and L-2-hydroxyglutarate panel - DBS

D2HG and L2HG Pnl DBS

Definition

  • This panel contains results for D-2-hydroxyglutarate (D-2-HG) and L-2-hydroxyglutarate (L-2-HG), the isomeric forms of 2-hydroxyglutaric acid. Accumulation of D-2-HG and/or L-2-HG in body fluids (e.g. urine, CSF, amniotic fluid, blood, plasma) are the biochemical hallmarks of 2-hydroxyglutaric acidurias (2-HGAs), inborn organic acidurias that cause neurological impairment at a young age.[PMID: 22391998] Results of this panel are used to differentiate D-2-HGA, L-2-HGA and D,L-2-HGA.

Component

  • D- & L-2-hydroxyglutarate panel

Specimen / system

  • Bld.dot

Class

  • PANEL.CHEM

Property

  • -

Scale

  • -

Related names

  • 2-hydroxy-glutarate; 2-hydroxyglutaric acid; 2OH-gluterate; alpha-Hydroxyglutarate; alpha-Hydroxyglutaric acid; Blood; Chemistry; D2HG and L2HG Pnl; DBS; Dextro; Dried blood spot; Filter paper; FP; Hydroxyglutaric aciduria; II; L2HG; L-2-HG; L2HGA; L-2-HGA; Left; Levo; Pan; PANEL.CHEMISTRY; Panl; Pnl; Point in time; Random; WB; Whole blood

Index terms

  • 2-hydroxy-glutarate
  • 2-hydroxyglutaric acid
  • 2OH-gluterate
  • alpha-Hydroxyglutarate
  • alpha-Hydroxyglutaric acid
  • Blood
  • Chemistry
  • D- & L-2-hydroxyglutarate panel
  • D2HG and L2HG Pnl
  • DBS
  • Dextro
  • Dried blood spot
  • Filter paper
  • FP
  • Hydroxyglutaric aciduria
  • II
  • L-2-HG
  • L-2-HGA
  • L2HG
  • L2HGA
  • Left
  • Levo
  • Pan
  • PANEL.CHEMISTRY
  • Panl
  • Pnl
  • Point in time
  • Random
  • WB
  • Whole blood