Zika virus IgM Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

ZIKV IgM CSF IA-aCnc

Definition

Quantitative analysis of Zika virus IgM antibodies in cerebral spinal fluid (CSF) specimens by immunoassay-based methods. Similar to most EIA tests, results are reported as a ratio of optical densities. Zika virus IgM antibodies become detectable 4-8 days after the onset of symptoms and persist for months. Since IgM does not normally cross the blood-brain barrier, detection of Zika virus IgM in CSF implies CNS infection. Serological cross-reactivity is strong between Zika and other flaviviruses, especially Dengue virus. Therefore, positive results for this test are presumptive and should be confirmed by neutralizing antibody testing [LOINC: 80621-6]. Negative results for this test on a sample taken during the first week of illness does not rule out infection and the test should be repeated on a convalescent sample.

ABS; Aby; Antby; Anti; Antibodies; Antibody; Arbitrary concentration; Autoantibodies; Autoantibody; Cerebral spinal fluid; Cerebrospinal Fl; EIA; ELFA; ELISA; Enzyme immunoassay; IAA; ID; Immune globulin M; Immunoglobulin M; Infectious Disease; InfectiousDisease; MEIA; Microbiology; Neuro; Neurology; Point in time; QNT; Quan; Quant; Quantitative; Random; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; SUDS; ZIKV