Zika virus neutralizing antibody [Titer] in Cerebral spinal fluid by Neutralization test --1st specimen

ZIKV NAb sp1 Titr CSF Nt

Definition

Quantitative result for Zika virus neutralizing antibodies in an acute phase CSF sample. Serological cross-reactivity is strong between Zika and other flaviviruses, especially Dengue virus. Therefore, positive EIA or IF assays for Zika virus IgM antibodies are presumptive only and should be confirmed by a neutralization assay, such as the plaque-reduction neutralization test (PRNT), which can discriminate between Zika virus and cross-reacting antibodies in primary flavivirus infections. Recent Zika virus infection is confirmed by stable high neutralizing antibody titers, seroconversion, or a 4x or greater increases in neutralizing antibody titer in a patient's appropriately timed acute and convalescent phase specimens.

ABS; Aby; Acute specimen; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Cerebral spinal fluid; Cerebrospinal Fl; Conventional virus neutralization test; cVNT; Dilution factor; Dilution Factor (Titer); First; ID; Infectious Disease; InfectiousDisease; Microbiology; NAb; Neuro; Neurology; NEUTRALIZATION; Neutralization test; NT; Point in time; Pre immunization; Random; Serum virus neutralization; SmQn; sp1; Spec; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; SVN; Titer; Titered; Titre; Ttr; Virus neutralization test; VNT; Zika virus Nab; ZIKV

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