81758-5

LOINC 2.82

Lymphocyte proliferation.anti-CD28.maximum/CD3 in Blood by Flow cytometry (FC)

LPT aCD28 max/CD3 NFr Bld FC

Definition

  • The percent of proliferating lymphocytes stimulated by anti-CD28 (aCD28) out of the total CD3+ T-cells. The maximum (highest proliferating out of 3 titrations) response to anti-CD28 is reported. This is a second-level test for assessing lymphocyte (T-cell) function after lymphocyte proliferation to phytohemagglutinin has been assessed. The test is used to evaluate patients with impairment in cellular immunity due to primary or secondary immunodeficiencies and in patients receiving immunosuppressive or immunomodulatory therapy.

Component

  • Lymphocyte proliferation.anti-CD28.maximum/CD3

Specimen / system

  • Bld

Class

  • HEM/BC

Property

  • NFr

Scale

  • Qn

Method

  • Flow cytometry

Related names

  • Blood; Dynamic; FC; HEMATOLOGY/CELL COUNTS; Leu4; Leu-4; LPA; LPT; LPT aCD28 max; LST; Lymphocyte antigen proliferation; Lymphocyte antigen stimulation; Number fraction; Percent; PHA; Point in time; QNT; Quan; Quant; Quantitative; Random; T3; T44; Tp44; WB; Whole blood

Index terms

  • Blood
  • Dynamic
  • FC
  • HEMATOLOGY/CELL COUNTS
  • Leu-4
  • Leu4
  • LPA
  • LPT
  • LPT aCD28 max
  • LST
  • Lymphocyte antigen proliferation
  • Lymphocyte antigen stimulation
  • Number fraction
  • Percent
  • PHA
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • T3
  • T44
  • Tp44
  • WB
  • Whole blood