Lymphocyte proliferation.anti-CD28.maximum/CD45 in Blood by Flow cytometry (FC)

LPT aCD28 max/CD45 NFr Bld FC

Definition

The percent of proliferating lymphocytes stimulated by anti-CD28 (aCD28) out of the total CD45 cell population. The maximum (highest proliferating out of 3 titrations) response to anti-CD28 is reported. This is a second-level test for assessing lymphocyte (T-cell) function after lymphocyte proliferation to phytohemagglutinin has been assessed. The test is used to evaluate patients with impairment in cellular immunity due to primary or secondary immunodeficiencies and in patients receiving immunosuppressive or immunomodulatory therapy.

B220; Blood; CD45R; CD45RA; CD45RB; CD45RC; CD45RO; Dynamic; FC; HEMATOLOGY/CELL COUNTS; LCA; Leukocyte common antigen; LPA; LPT; LPT aCD28 max; LST; Ly5; Lymphocyte antigen proliferation; Lymphocyte antigen stimulation; Number fraction; Percent; PHA; Point in time; QNT; Quan; Quant; Quantitative; Random; T200; T44; Tp44; WB; Whole blood