Human papilloma virus 16 and 18+45 E6+E7 mRNA [Identifier] in Cervix by NAA with probe detection

HPV16+18+45 E6+E7mRNA Cvx NAA+probe

Definition

Detects E6/E7 viral messenger RNA (mRNA) of human papillomavirus (HPV) types 16, 18, and 45 in cervical specimens from women with positive HPV assay results. For women 21-years and older with atypical squamous cells of undetermined significance (ASC-US) cervical cytology results, and HPV positive assay results, this assay can be used to assess the presence or absence of high-risk HPV genotypes 16, 18, and/or 45. For women 30-years and older, the HPV 16, 18, and/or 45 genotype assay can be used to test samples from women with HPV assay positive results, along with cervical cytology results. This assay has not been evaluated for HPV vaccinated patients or in cases of suspected abuse. It differentiates HPV 16 from HPV 18 and/or HPV 45, but does not differentiate HPV 18 and HPV 45. This term was created for, but not limited in use to, the Aptima HPV 16 18/45 genotype assay which uses target capture, target amplification by transcription-mediated amplification and detection of the amplification products by hybridization protection assay (HPA).

3 Self-Sustaining Sequence Replication; 3SR SR; Amplif; Amplification; Amplified; Cervix; DNA NUCLEIC ACID PROBE; DNA probe; Genital tract; Genital warts; Gyn; Gynecology; HPV; HPV 16 & 18+45; HPV16; HPV16 and 18; HPV16+18; HPV16+18+45 E6+E7mRNA; Human papillomavirus; ID; Identity or presence; Infectious Disease; InfectiousDisease; LAT; LCR; Ligase chain reaction; Ligation-activated transcription; Microbiology; NAA+probe; NAAT; NASBA; Nominal; Nucleic acid sequence based analysis; OB; ObGyn; Obstetrics; Papilloma virus high risk; PCR; Point in time; Polymerase chain reaction; Probe amp; Probe with ampification; Probe with target amplification; QBR; Random; SDA; Strand Displacement Amplification; TMA; Transcription mediated amplification

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