U1 small nuclear ribonucleoprotein C Ab [Presence] in Serum by Line blot

U1 snRNP-C Ab Ser Ql Line blot

Definition

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Mixed connective tissue disorder; Nuc; Ordinal; Point in time; PR; QL; Qual; Qualitative; Random; Raynaud's Disease; Rh Blood Group System; Ribonuclear protein; RNP; Screen; Serology; Serum; snRNP; snRPC; SR; Systemic lupus erythematosus; U1 RNP; U1 snRNP; U1 snRNP-C; U1RNP