82530-7

LOINC 2.82

SDHB gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method

SDHB gene Del+Dup + Full Mut Anl Bld/T

Definition

  • Full sequencing analysis of all 8 coding exons and intron/exon boundaries of the SDHB gene is performed along with large deletion/duplication analysis.[OMIM: 185470][NCBI Gene ID: 6390] This test is performed to aid in the diagnosis of hereditary paraganglioma-pheochromocytoma syndrome associated with pathogenic SDHB gene variants.

Component

  • SDHB gene deletion+duplication & full mutation analysis

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH.MUT

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • Amplification; Blood; CWS2; Del; Del+Dup; Del+Dup + Full Mut Anl; Deletions; Document; Dp; Finding; Findings; full gene sequencing; Full Mut Anl; Genetics; Heredity; Heritable; Inherited; IP; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Mut; Mutations; PCR; PGL4; Point in time; Random; SDH; SDH1; SDHIP; sequencing of entire coding region; Succinate dehydrogenase complex, subunit B, iron sulfur; succinate dehydrogenase complex, subunit B, iron sulfur (Ip); Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • Amplification
  • Blood
  • CWS2
  • Del
  • Del+Dup
  • Del+Dup + Full Mut Anl
  • Deletions
  • Document
  • Dp
  • Finding
  • Findings
  • full gene sequencing
  • Full Mut Anl
  • Genetics
  • Heredity
  • Heritable
  • Inherited
  • IP
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • MOLPATH.MUTATIONS
  • Mut
  • Mutations
  • PCR
  • PGL4
  • Point in time
  • Random
  • SDH
  • SDH1
  • SDHB gene deletion+duplication & full mutation analysis
  • SDHIP
  • sequencing of entire coding region
  • Succinate dehydrogenase complex, subunit B, iron sulfur
  • succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
  • Tissue
  • Tissue, unspecified
  • WB
  • Whole blood
  • Whole blood or Tissue