82532-3

LOINC 2.82

SDHB and SDHC and SDHD gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method

SDHB+SDHC+SDHD Del+Dup + Full Mut Bld/T

Definition

  • Full sequencing analysis of all coding exons and intron/exon boundaries of the SDHB, SDHC and SDHD genes is performed along with large deletion/duplication analysis by methods such as multiplex ligation-dependent probe amplification (MLPA). This test is performed to aid in the diagnosis of hereditary paraganglioma-pheochromocytoma syndrome associated with pathogenic variants in one of these genes.

Component

  • SDHB & SDHC & SDHD gene deletion+duplication & full mutation analysis

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • Amplification; Blood; CBT1; CII-4; CWS3; cybS; Del; Del+Dup; Del+Dup + Full Mut Anl; Deletions; Document; Dp; Finding; Findings; full gene sequencing; Full Mut Anl; Genetics; Heredity; Heritable; Inherited; Molecular genetics; Molecular pathology; MOLPATH; Mut; Mutations; paraganglioma or familial glomus tumors 1; PCR; PGL; PGL1; Point in time; QPs3; Random; SDH4; SDHB+SDHC+SDHD; sequencing of entire coding region; succinate dehydrogenase complex, subunit D, integral membrane protein; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • Amplification
  • Blood
  • CBT1
  • CII-4
  • CWS3
  • cybS
  • Del
  • Del+Dup
  • Del+Dup + Full Mut Anl
  • Deletions
  • Document
  • Dp
  • Finding
  • Findings
  • full gene sequencing
  • Full Mut Anl
  • Genetics
  • Heredity
  • Heritable
  • Inherited
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • Mut
  • Mutations
  • paraganglioma or familial glomus tumors 1
  • PCR
  • PGL
  • PGL1
  • Point in time
  • QPs3
  • Random
  • SDH4
  • SDHB & SDHC & SDHD gene deletion+duplication & full mutation analysis
  • SDHB+SDHC+SDHD
  • sequencing of entire coding region
  • succinate dehydrogenase complex, subunit D, integral membrane protein
  • Tissue
  • Tissue, unspecified
  • WB

2 further terms