82741-0

LOINC 2.82

Pediatric autoimmune neuropsychiatric disorder associated with streptococcus (PANDAS) panel - Serum

PANDAS panel Ser

Definition

  • PANDAS (pediatric autoimmune neuropsychiatric disorder associated with streptococcus infection) is a condition in which some children experience a sudden onset or worsening of neuropsychiatric symptoms, such as OCD and tics, following a group A streptococcus infection. There is correlational evidence that PANDAS may be triggered by an autoimmune response to the streptococcus infection. The anti-dopamine, anti-lysoganglioside, and anti-beta tubulin antibodies produced by the immune system in response to the streptococcus infection is associated with higher activation of CaM-Kinase II, which may disrupt neurologic activity in the basal ganglia.[NCBI Books:NBK333433][PMID:12204920]

Component

  • Pediatric autoimmune neuropsychiatric disorder associated with streptococcus diagnosis panel

Specimen / system

  • Ser

Class

  • PANEL.SERO

Property

  • -

Scale

  • -

Related names

  • Assoc; Dx; Pan; PANDAS panel; PANEL.SEROLOGY; Panl; PEDS; Pnl; Point in time; Random; Serology; Serum; SR; Strep; Strept

Index terms

  • Assoc
  • Dx
  • Pan
  • PANDAS panel
  • PANEL.SEROLOGY
  • Panl
  • Pediatric autoimmune neuropsychiatric disorder associated with streptococcus diagnosis panel
  • PEDS
  • Pnl
  • Point in time
  • Random
  • Serology
  • Serum
  • SR
  • Strep
  • Strept