Cells.chromosome 7 monosomy/Cells counted in Blood or Tissue by FISH

Cells.Chr Mono 7/Cells NFr Bld/T FISH

Definition

The percent of cells in blood or tissue containing a single copy of chromosome 7 (monosomy 7) can be detected by FISH based on the number of chromosome 7 probe signals and used for the diagnosis of acute myeloid leukemia or myelodysplastic syndrome. This term is used to report the number of cells that have a chromosome 7 deletion out of total number of cells examined (e.g. 80 out of 100 cells, or 80%). Results are also typically reported in ISCN (International System for Human Cytogenetic Nomenclature) format [LOINC: 62356-1]. This term is based, but not limited in use to, the Vysis LSI D7S486(7q31)/CEP 7(7p11.1-q11.1) probe kit. To report percentage results for the 7q31 (D7S486) probe deletion, used [LOINC: 84921-6].

Blood; Cell; Cells.Chr Mono 7; Cellularity; Chromosom; Chromosomes; Fluorescent in situ hybridization; Genetics; Heredity; Heritable; Inherited; Molecular pathology; MOLPATH; MOLPATH.DELDUP; Number Fraction; Percent; Point in time; QNT; Quan; Quant; Quantitative; Random; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue