Liver diseases autoimmune IgG panel - Serum or Plasma by Line blot

Liver diseases IgG Pnl SerPl Line blot

Definition

This panel contains results for the presence of IgG autoantibodies in serum or plasma for the diagnosis of autoimmune liver diseases, including autoimmune hepatitis and primary biliary cirrhosis. This panel was created for, but not limited in use to, the submitter's test strip, a membrane strip pre-coated with the following antigens: AMA-M2, M2-3E, Sp100, PML, gp210, LKM-1, LC-1, SLA/LP, SS-A, Ro-52, Scl-70, CENP A, CENP B and PGDH. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Various manufacturers classify this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

Immune globulin G; Immunoglobulin G; Liver diseases IgG Pnl; Pan; PANEL.SEROLOGY; Panl; Pl; Plasma; Plsm; Pnl; Point in time; Random; Serology; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR