85100-6

LOINC 2.82

FLT3 gene internal tandem duplication [Presence] in Bone marrow by Molecular genetics method

FLT3 ITD Dp Mar Ql

Definition

  • Detection of an FLT3 internal tandem duplication (ITD) mutation in bone marrow for the diagnosis of acute myeloid leukemia (AML). The FLT3 wild type alleles produce a fragment that is approximately 327 +/-1 base pair (bp), while alleles containing an ITD mutation will produces a fragment that is approximately >=330 bp.

Component

  • FLT3 gene internal tandem duplication

Specimen / system

  • Bone mar

Class

  • MOLPATH.MUT

Property

  • PrThr

Scale

  • Ord

Method

  • Molgen

Related names

  • Amplification; BM; BON; Bone marrow; CD135; Dp; FL cytokine receptor precursor; FLK2; FLK-2; FLT3 ITD; fms-like tyrosine kinase 3; fms-related tyrosine kinase 3; Genetics; Heredity; Heritable; Inherited; MAR; Marrow (bone); minimal angle of resolution; Minimum angle of resolution; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; Ordinal; PCR; Point in time; PR; QL; Qual; Qualitative; Random; Screen; Stem cell tyrosine kinase 1; STK1; STK-1

Index terms

  • Amplification
  • BM
  • BON
  • Bone marrow
  • CD135
  • Dp
  • FL cytokine receptor precursor
  • FLK-2
  • FLK2
  • FLT3 ITD
  • fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • Genetics
  • Heredity
  • Heritable
  • Inherited
  • MAR
  • Marrow (bone)
  • minimal angle of resolution
  • Minimum angle of resolution
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • MOLPATH.MUTATIONS
  • Ordinal
  • PCR
  • Point in time
  • PR
  • QL
  • Qual
  • Qualitative
  • Random
  • Screen
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1