Borrelia afzelii+burgdorferi+garinii IgG band pattern [Interpretation] in Serum by Line blot

B afz+burg+gari IgG Ptrn Ser Ln blot

Definition

The pattern of reactive bands specific to IgG antibodies associated with Borrelia afzelii, B burgdorferi, and B garinii species in human serum. Antibodies against p83, p58, p43, p39, p30, OspC, p21, Osp17/DbpA, p14 and VlsE antigens are characterized as highly specific for Borrelia species. The presence of specific bands suggests a recent infection of Lyme disease.This term was created for, but not limited in use to, the Borrelia ViraStripe IgG assay, which uses native, purified antigens immobilized on a test strip to which patient antibodies, if present, will bind. Various manufacturers label this method as an immunoblot technique. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the laboratory assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method is Line blot.

ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; B afz+burg+gari; B afzelii; Bands; bnd; ID; IgG Patrn; Immune globulin G; Immunoglobulin G; Impression; Impression/interpretation of study; Impressions; Infectious Disease; InfectiousDisease; Interp; Interpretation; Microbiology; Nominal; Patrn; Point in time; Random; Serum; SR