IgA, IgA1 and IgA2 panel - Serum or Plasma

IgA + IgA1 + IgA2 Pnl SerPl

Definition

This panel contains quantitative results for IgA and IgA subclasses 1 and 2 in serum. IgA1 is the dominant subclass, accounting for over 80% of total serum IgA. IgA2 is more concentrated in secretions and thought to be more functionally active than IgA1. IgA testing may be performed for the diagnosis of abnormal protein metabolism, to determine the cause of an immune deficiency due to an IgA deficiency, or to determine the cause of an anaphylactic transfusion reaction. Such patients are found to have no detectable levels of IgA or complete deficiency of one of the IgA subclasses. A deficiency in one IgA subclass may result in a corresponding increase in the other IgA subclass. When very high levels of either IgA subclass are reported, IgA myeloma is suspected.

Chemistry; i; IgA + IgA1 + IgA2 Pnl; IgA1; IgA2; II; Immune globulin A; Immunoglobulin A; Pan; PANEL.CHEMISTRY; Panl; Pl; Plasma; Plsm; Pnl; Point in time; QNT; Quan; Quant; Quantitative; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; Subclasses