89041-8

LOINC 2.82

Lung cancer antibody [Interpretation] in Serum or Plasma by Immunoassay

Lung cancer antibody SerPl IA-Imp

Definition

  • Screening for lung cancer using computerized tomography (CT) has been shown to decrease mortality by 20%. CT is an expensive procedure that also can reveal non-malignant changes on the chest CT. The EarlyCDT-Lung assay is a cheaper alternative with fairly good sensitivity and specificity for detecting early, asymptomatic non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). To achieve the desired specificity of 90%, the autoantibody cutoff values were chosen based on that goal. The overall sensitivity/specificity of the assay was determined to be 38%/88%. When the sensitivity and specificity were measured based on the type of tumor, NSCLC was 34%/88% and SCLC was 50%/88%.[http://cancerpreventionresearch.aacrjournals.org/content/4/7/1126.long#ref-1]

Component

  • Lung cancer antibody

Specimen / system

  • Ser/Plas

Class

  • SERO

Property

  • Imp

Scale

  • Nom

Method

  • IA

Related names

  • Ab; EIA; ELFA; ELISA; Enzyme immunoassay; IAA; Impression; Impression/interpretation of study; Impressions; Interp; Interpretation; Lung cancer Ab; MEIA; Nominal; Pl; Plasma; Plsm; Point in time; Random; Serology; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR; SUDS

Index terms

  • Ab
  • EIA
  • ELFA
  • ELISA
  • Enzyme immunoassay
  • IAA
  • Impression
  • Impression/interpretation of study
  • Impressions
  • Interp
  • Interpretation
  • Lung cancer Ab
  • MEIA
  • Nominal
  • Pl
  • Plasma
  • Plsm
  • Point in time
  • Random
  • Serology
  • SerP
  • SerPl
  • SerPlas
  • Serum
  • Serum or plasma
  • SR
  • SUDS