SCL-70 extractable nuclear Ab [Units/volume] in Serum by Line blot

ENA Scl70 Ab Ser Line blot-aCnc

Definition

This term was created for, but is not limited in use to, the submitter's test strip, a membrane strip pre-coated with a specific set of antigens in parallel lines. If antibodies to any of those antigens are present in the patient's serum, they will bind to the specific antigen. The bound patient antibodies are then detected using labelled anti-human antibodies. Manufacturers call this method by different names, including immunoblot, line blot, and line immunoassay. LOINC uses the immunoblot (IB) method to mean that some electrophoretic/chromatographic separation occurs such that position (size) of the band is part of the assessment (as in Western blot). Because this assay does not involve a separation step but rather uses strips with pre-fixed antigens, the LOINC Method for this term is Line blot.

ABS; Aby; ANA; ANF; Antby; Anti; Antibodies; Antibody; Antinuclear antibody; anti-topo I; Arbitrary concentration; Autoantibodies; Autoantibody; DNA-Topoisomerase I; ENA; ENA Scl70; NA; Nuc; Point in time; QNT; Quan; Quant; Quantitative; Random; Scleroderma; Scleroderma ab; Serology; Serum; SR; Topo I; Topoisomerase I