90735-2

LOINC 2.82

PNH GPI-Linked WBC and RBC Ag Panel - Blood

PNH GPI-Lkd WBC + RBC Ag Pnl Bld

Definition

  • The tests in this panel detect glycosylphosphatidylinositol (GPI)-linked proteins including CD14 for monocytes, CD16 and 24 for granulocytes, and CD59 for erythrocytes. In addition, fluorescent aerolysin (FLAER) which selectively binds to GPI anchor proteins, is also used to detect the presence or absence of those anchors. Paroxysmal nocturnal hemoglobinuria (PNH) is an acquired hematologic disorder of erythroid, granulocytic, and megakaryocytic cell lines. The abnormal cells in PNH are missing the GPI-linked proteins due to mutations in the phosphatidylinositol glycan A gene (PIGA).

Component

  • Paroxysmal nocturnal hemoglobinuria GPI-Linked WBC & RBC Ag Panel

Specimen / system

  • Bld

Class

  • PANEL.CELLMARK

Property

  • -

Scale

  • -

Related names

  • Blood; CELL MARKERS; Glycosylphosphatidylinositol-linked proteins; Pan; PANEL.CELLMARK; Panl; Paroxysmal nocturnal hemoglobinuria; PLINK; PNH; PNH GPI-Linked WBC + RBC; PNH GPI-Lkd WBC + RBC Ag; PNH GPI-Lkd WBC + RBC Ag Pnl; Pnl; Point in time; Random; WB; Whole blood

Index terms

  • Blood
  • CELL MARKERS
  • Glycosylphosphatidylinositol-linked proteins
  • Pan
  • PANEL.CELLMARK
  • Panl
  • Paroxysmal nocturnal hemoglobinuria
  • Paroxysmal nocturnal hemoglobinuria GPI-Linked WBC & RBC Ag Panel
  • PLINK
  • PNH
  • PNH GPI-Linked WBC + RBC
  • PNH GPI-Lkd WBC + RBC Ag
  • PNH GPI-Lkd WBC + RBC Ag Pnl
  • Pnl
  • Point in time
  • Random
  • WB
  • Whole blood