92844-0

LOINC 2.82

FLT3 gene internal tandem duplication/Normal [Ratio] in Blood or Tissue by Molecular genetics method

FLT3 ITD Dp/Nor Bld/T-Rto

Definition

  • This term represents a ratio (allelic ratio), following PCR amplification, of a patient's FLT3 gene DNA having internal tandem duplication to that same patient's wild type FLT3 gene DNA not having such duplication. The result is expressed as a signal ratio of peak band intensities and correlates to cells with and without mutated DNA. A ratio of 100.00 is the maximum and indicates a patient specimen has 100% FLT3-mutated tumor with no healthy cells. A ratio between 0.03 and 0.05 indicates low levels of disease.

Component

  • FLT3 gene internal tandem duplication/normal

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH.MUT

Property

  • Ratio

Scale

  • Qn

Method

  • Molgen

Related names

  • Amplification; Blood; CD135; Control; Dp; FL cytokine receptor precursor; FLK2; FLK-2; FLT3 ITD; fms-like tyrosine kinase 3; fms-related tyrosine kinase 3; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.MUTATIONS; PCR; Point in time; QNT; Quan; Quant; Quantitative; Random; Ratios; Rto; Stem cell tyrosine kinase 1; STK1; STK-1; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • Amplification
  • Blood
  • CD135
  • Control
  • Dp
  • FL cytokine receptor precursor
  • FLK-2
  • FLK2
  • FLT3 ITD
  • fms-like tyrosine kinase 3
  • fms-related tyrosine kinase 3
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • MOLPATH.MUTATIONS
  • PCR
  • Point in time
  • QNT
  • Quan
  • Quant
  • Quantitative
  • Random
  • Ratios
  • Rto
  • Stem cell tyrosine kinase 1
  • STK-1
  • STK1
  • Tissue
  • Tissue, unspecified
  • WB
  • Whole blood
  • Whole blood or Tissue