93198-0

LOINC 2.82

10q23 g.94645745G>A [Genotype] in Blood or Tissue by Molecular genetics method Nominal

10q23 g.94645745G>A Geno Bld/T

Definition

  • The non-coding variant g.94645745G>A (rs12777823) located in the CYP2C cluster near the CYP2C18 gene on chromosome 10 is associated with warfarin dosing among African Americans (mainly originating from West Africa). For those with rs12777823 A/G or A/A genotypes, a warfarin dose reduction of 10-25% is recommended.[PMID: 28198005]

Component

  • 10q23 g.94645745G>A

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH.PHARMG

Property

  • Geno

Scale

  • Nom

Method

  • Molgen

Related names

  • Blood; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.PHARMG; NC_000010.10:g.96405502G>A; NC_000010.11:g.94645745G>A; Nominal; PCR; Point in time; Random; rs12777823; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • A
  • Blood
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • MOLPATH.PHARMG
  • NC_000010.10:g.96405502G&gt
  • NC_000010.11:g.94645745G&gt
  • Nominal
  • PCR
  • Point in time
  • Random
  • rs12777823
  • Tissue
  • Tissue, unspecified
  • WB
  • Whole blood
  • Whole blood or Tissue