Coronary heart disease multigene analysis in Blood or Tissue by Molecular genetics method

CHD Multigene Anl Bld/T

Definition

This test includes analysis of alleles at multiple genetic loci associated with coronary heart disease (CHD). Testing is performed to determine an individual's genetic-based risk for CHD, particularly in patients at intermediate risk for atherosclerotic cardiovascular disease (ASCVD) and those with family history of ASCVD. An overall genetic risk score (GRS) [LOINC: 93306-9] and interpretation (high/low) [LOINC: 93307-7] may be provided to improve risk estimates and aid in the prevention of CHD. The GRS is based on the genotype of multiple genetic variants associated with CHD. Additionally, a patient's overall 10-year probability of CHD may be calculated by multiply the 10-year ASCVD score from the Pooled Cohort Equations by the GRS.

Blood; CHD Multigene Anl; Dis; Diseases; Document; Dz; Finding; Findings; Gene; Gene panel; Molecular genetics; Molecular pathology; MOLPATH; Multi-gene study; Multiple-gene panel test; PCR; Point in time; Random; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue