93813-4

LOINC 2.82

NTRK1, NTRK2 and NTRK3 gene rearrangements in Tissue by Molecular genetics method

NTRK1+NTRK2+NTRK3 rearr Tiss

Definition

  • This test detects fusions (rearrangements) involving the NTRK1, NTRK2, and NTKR3 genes to identify solid tumors that may respond to NTRK-targeted therapies. These NTRK genes rearrange with more than 80 fusion gene partners, leading to tumorigenesis across a variety of tumor types.[PMID: 31075511] The collection of information contained by this term may include the test method(s), targeted fusion variants, the overall result (fusion variant detected/not detected), the fusion variant identified, the interpretation, recommendations, references and clinical trial information.

Component

  • NTRK1 gene & NTRK2 gene & NTRK3 gene rearrangements

Specimen / system

  • Tiss

Class

  • MOLPATH.PHARMG

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • Document; Finding; Findings; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.PHARMG; NTRK1+NTRK2+NTRK3; NTRK1+NTRK2+NTRK3 rearr; PCR; Point in time; Random; Rearr; Rearrangement; Tissue; Tissue, unspecified

Index terms

  • Document
  • Finding
  • Findings
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • MOLPATH.PHARMG
  • NTRK1 gene & NTRK2 gene & NTRK3 gene rearrangements
  • NTRK1+NTRK2+NTRK3
  • NTRK1+NTRK2+NTRK3 rearr
  • PCR
  • Point in time
  • Random
  • Rearr
  • Rearrangement
  • Tissue
  • Tissue, unspecified