94197-1

LOINC 2.82

CYP21A2 gene deletion+duplication and full mutation analysis in Blood or Tissue by Molecular genetics method

CYP21A2 Del+Dup + Full Mut Anl Bld/T

Definition

  • Test includes full sequence analysis (e.g. by Sanger and/or next-generation sequencing) and deletion/duplication analysis (e.g. by multiplex ligation-dependent probe amplification) to evaluate for mutations and large deletions/duplications in the CYP21A2 gene. Testing is performed for carrier screening and diagnosis of 21-hydroxylase deficient congenital adrenal hyperplasia (CAH).

Component

  • CYP21A2 gene deletion+duplication & full mutation analysis

Specimen / system

  • Bld/Tiss

Class

  • MOLPATH

Property

  • Find

Scale

  • Doc

Method

  • Molgen

Related names

  • 21 Hydroxylase Deficiency; Amplification; Blood; CA21H; CAH1; Congenital adrenal hyperplasia; CPS1; CYP21; CYP21B; cytochrome P450, family 21, subfamily A, polypeptide 2; Del; Del+Dup; Del+Dup + Full Mut Anl; Deletions; Document; Dp; Finding; Findings; full gene sequencing; Full Mut Anl; Genetics; Heredity; Heritable; Inherited; Molecular genetics; Molecular pathology; MOLPATH; Mut; Mutations; P450c21B; PCR; Point in time; Random; sequencing of entire coding region; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue

Index terms

  • 21 Hydroxylase Deficiency
  • Amplification
  • Blood
  • CA21H
  • CAH1
  • Congenital adrenal hyperplasia
  • CPS1
  • CYP21
  • CYP21A2 gene deletion+duplication & full mutation analysis
  • CYP21B
  • cytochrome P450, family 21, subfamily A, polypeptide 2
  • Del
  • Del+Dup
  • Del+Dup + Full Mut Anl
  • Deletions
  • Document
  • Dp
  • Finding
  • Findings
  • full gene sequencing
  • Full Mut Anl
  • Genetics
  • Heredity
  • Heritable
  • Inherited
  • Molecular genetics
  • Molecular pathology
  • MOLPATH
  • Mut
  • Mutations
  • P450c21B
  • PCR
  • Point in time
  • Random
  • sequencing of entire coding region
  • Tissue
  • Tissue, unspecified
  • WB
  • Whole blood
  • Whole blood or Tissue