94266-4LOINC 2.82
CD11a, CD11b, and CD18 phenotyping panel - Blood Qualitative
CD11a + CD11b + CD18 Pnl Bld
Definition
- Flow cytometric immunophenotyping evaluation for presence or absence of the CD11/CD18 complex using monoclonal antibodies directed against the CD11 isoforms, CD11a and CD11b, and CD18 antigens. Defects in CD18 expression lead to either very low or no surface membrane expression of alpha chains CD11a, CD11b, and CD11c. Testing is performed for the diagnosis of leukocyte adhesion deficiency syndrome type 1 (LAD-1), an autosomal recessive disorder caused by mutations in the common chain (CD18) of the beta2-integrin family.
Component
- CD11a & CD11b & CD18 phenotyping panel
Specimen / system
- Bld
Class
- PANEL.CELLMARK
Property
- -
Scale
- Ord
Related names
- AlphaL integrin chain; AlphaM integrin chain; AlphaM-beta2; Beta2; Beta-2 integrin; Beta-2 integrin chain; Blood; C3biR; CD11a + CD11b + CD18 Pnl; CD11a beta subunit; CD11b beta subunit; CD11c beta subunit; CELL MARKERS; CR3; LAD-1; Leu15; Leu-15; Leukocyte Adhesion Deficiency Syndrome; Leukocyte adhesion deficiency syndrome type 1; LFA-1alpha; Mac-1; Mo1; Ordinal; Pan; PANEL.CELLMARK; Panl; Pheno; Phenotypic; Pnl; Point in time; QL; Qual; Qualitative; R3; Random; Screen; WB; Whole blood
Index terms
- AlphaL integrin chain
- AlphaM integrin chain
- AlphaM-beta2
- Beta-2 integrin
- Beta-2 integrin chain
- Beta2
- Blood
- C3biR
- CD11a & CD11b & CD18 phenotyping panel
- CD11a + CD11b + CD18 Pnl
- CD11a beta subunit
- CD11b beta subunit
- CD11c beta subunit
- CELL MARKERS
- CR3
- LAD-1
- Leu-15
- Leu15
- Leukocyte Adhesion Deficiency Syndrome
- Leukocyte adhesion deficiency syndrome type 1
- LFA-1alpha
- Mac-1
- Mo1
- Ordinal
- Pan
- PANEL.CELLMARK
- Panl
- Pheno
- Phenotypic
- Pnl
- Point in time
- QL
- Qual
- Qualitative
- R3
- Random
- Screen
- WB
- Whole blood