HLA-DP and DQ and DR (class II) IgG high risk [Identifier] in Serum or Plasma by Flow cytometry (FC)

HLA class II Ab.IgG high risk SerPl FC

Definition

Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in the higher risk stratification of MFI values (For one lab this was MFI > 5000, but some laboratories use 10,000 or another value).

2; Dynamic; FC; Genetics; Heredity; Heritable; HLA ANTIGEN; HLA class II; HLA class II Ab.IgG high risk; HLA-DP+DQ+DR; HLA-DP+DQ+DR (class II); Human Leukocyte Antigen; Identity or presence; Immune globulin G; Immunoglobulin G; Inherited; Nominal; Pl; Plasma; Plsm; Point in time; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR