HLA-A and B and C (class I) IgG intermediate risk [Identifier] in Serum or Plasma by Flow cytometry (FC)

HLA class I Ab.IgG med risk SerPl FC

Definition

Laboratories that perform HLA antibody testing often report the specific antibodies found in categories based on the "amount" of each antibody found (called mean fluorescent intensity, MFI, for the common Luminex bead method). Theoretically, the antibodies present in higher concentrations, which are more likely to react with donor antigens, will have higher MFI values. Since risk stratification based on MFI range is not standardized and the exact cutoffs vary from lab to lab, this term is intended to report those HLA antibodies found in an intermediate risk stratification of MFI values (For one lab this was 4999 > MFI > 2000, but some laboratories use other values).

A,B; Dynamic; FC; Genetics; Heredity; Heritable; HLA ANTIGEN; HLA class I; HLA class I Ab.IgG med risk; HLA-A+B; HLA-A+B+C; HLA-A+B+C (class I); Human Leukocyte Antigen; Identity or presence; Immune globulin G; Immunoglobulin G; Inherited; Nominal; Pl; Plasma; Plsm; Point in time; Random; SerP; SerPl; SerPlas; Serum; Serum or plasma; SR