Psychotropic medication pharmacogenomic analysis in Blood or Tissue by Molecular genetics method

Psychotropic Pharmg Analy Bld/T

Definition

A comprehensive analysis for multiple genes that have strong pharmacogenomic associations with medications used in the treatment of psychiatric disorders, including depression. Each sample is tested for specific genetic variations with known functional impact. Depending on the lab, this test may include targeted analysis for following genes: ANKK1, ADRA2, CHRNA3, COMT, CYP1A2, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP3A4, CYP3A5, DRD2, EPHX1, GRIK4, HLA-A (such as HLA-A*31:01 allele), HLA-B (such as HLA-B*15:02 allele), HTR2A, HTR2C, MTHFR, OPRM1, SCN1A, SLC6A4 (5-HTT), and UGT2B15. Duplications and multiplications of alleles may also be identified. Various genotyping assay methods, such as real-time PCR, sequencing, and deletion/duplication analysis, may be used.

Blood; Document; Finding; Findings; Genetics; Heredity; Heritable; Inherited; Molecular genetics; Molecular pathology; MOLPATH; MOLPATH.PHARMG; PCR; Point in time; Psychotropic medications panel; Psychotropic pharmacogenomics; Psychotropic Pharmg Analy; Random; Tissue; Tissue, unspecified; WB; Whole blood; Whole blood or Tissue