Chromosome 1q and 9 and 11 and 15 aneuploidy and 13q deletion in Bone marrow by FISH

Chr 1q+9+11+15 aneu 13q Del Mar FISH

Definition

The detection by FISH analysis of gains (duplications, aneuploidy) and losses (deletion or monosomy) of chromosome regions (e.g. 1q, 13q, 9, 11 and 15) associated with multiple myeloma. This study is performed to determine the prognostic risk for disease outcome. For example, gains of chromosome 1q and monosomy or deletions of 13q are associated with less favorable outcomes whereas gains of chromosome 9, 11, and 15 are associated with more favorable outcomes.

BM; BON; Bone marrow; Chr 1q+9+11+15 aneu 13q; Chr 1q+9+11+15 aneu 13q Del; Chromosom; Chromosomes; Cyto loc; Del; Deletions; Document; Finding; Findings; Fluorescent in situ hybridization; Genetics; Heredity; Heritable; Inherited; MAR; Marrow (bone); minimal angle of resolution; Minimum angle of resolution; Molecular pathology; MOLPATH; MOLPATH.DELDUP; Point in time; Random